Camusso began her trade-union career at FIOM, the Federation of Engineering Workers in 1975. In 1997 she was elected secretary general of FLAI Lombardia, the Federation of Agro-Industry Workers and since 2001 she has been secretary general of Cgil Lombardia.
In 2005 she founded the movement “Usciamo dal silenzio” in defense of women’s freedom, and in 2006 she organized a national demonstration with 200 thousand people in defense of Italian Law 194 on the voluntary interruption of pregnancy.